This is from an obscure source in the Ukraine, but may be of some interest. They combined a technique of electrically stimulating the rectal muscles with an antidepressant (sertraline / Zoloft).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469008/
Unfortunately not randomised placebo controlled etc.
Rectal electrostimulation + antidepressant
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Rectal electrostimulation + antidepressant
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