When I read this, I groaned. No serious researcher would jump to such a conclusion. Firstly, is CPPS an autoimmune disease? Probably not. Secondly, these are rodents, not people. And they have an induced autoimmune condition, nothing like what men with UCPPS have.In this study, we confirmed that iMSCs-EVs administration could effectively ameliorate chronic pelvic pain, reduce voiding pressure, increase the intercontraction interval, suppress inflammatory reactions and promote prostatic tissue repair.
There is a section on T helper cell (Th1/Th2 and Treg/Th17) re-regulation. It's a bit vague, but interesting.
I am more hopeful that the COX-2 aspect is fruitful, and I await human trials.These data illuminated that iMSCs-EVs could ameliorate chronic pelvic pain by downregulating the overexpression of COX-2.