UCPPS - Prostatitis, Interstitial Cystitis Forum

Bottom line: You have to take them for a few months to see if they work Systematic Review of Alpha Blockers for the Treatment of Pain in Chronic Prostatitis Anthony M. Carona, University of Houston College of Medicine Introduction: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a dis...

Fails for prostate cancer , that is. Because DRE has been such a "go-to" test for so many decades, I thought this is worth posting. Cancer detection rate by PSA is four times higher compared to the DRE detection. Around 18% of the tumors are located in the part of the prostate where DRE c...

Interestingly, urticaria and Bladder Pain Syndrome are linked http://www.ncbi.nlm.nih.gov/pubmed/36343865 In patients with interstitial cystitis or bladder pain syndrome (IC/BPS), 85% were found to have pelvic floor myofascial pain and hypertonicity. However, physicians are not typically trained to ...

Social problem solving as a mediator of stress and chronic prostatitis symptomology PMID: 36267040 DOI: 10.1080/13548506.2022.2132410 Social problem solving (SPS), the process by which individuals attempt to cope with stressful life problems, has previously been found to mediate the relationship be...

Men With Chronic Orchialgia Exhibit Differential Neuroinflammatory Gene Expression Relative to Asymptomatic Controls https://pubmed.ncbi.nlm.nih.gov/35644304/ Translation: men with UCPPS whose main symptom is chronic testicle pain differ from 'normal' men in that genes controlling nerve inflammatio...

Men with chronic orchialgia (testicle pain) have nerve-inflaming genes that work differently to normal men, and they can benefit from denervation surgery:
https://www.sciencedirect.com/science/a ... 9522004344

Efficacy of pulsed electromagnetic field (PEMF) therapy for pelvic pain reduction and symptom improvement in interstitial cystitis: A pilot study https://app.swapcard.com/event/2022-aua-annual-meeting-new-orleans/planning/UGxhbm5pbmdfODc5MTQ0 Patients who catastrophize less throughout treatment have...

Well, n=1 , but I have had a report from an old friend that treatment with omalizumab injections has removed his UCPPS. Here is a list of what is gone: CPPS (I can’t detect it now). Asthma. All allergies to pollen, dust, dander. Dermographism. Urticaria. Itching. I thought I'd note it here for futur...

Men without a history of pelvic pain were able to relax their pelvic floor muscles back to baseline after performing voluntary pelvic floor muscle contractions. In contrast, men with CP/CPPS, particularly those with ejaculation-related pain, had an impaired ability to relax their pelvic floor muscl...

https://www.asbmb.org/asbmb-today/science/051022/how-chronic-pain-shows-up-in-urine Using protein signatures in urine, researchers have been able to distinguish UCPPS from other chronic pain diseases, including myalgic encephalomyelitis/chronic fatigue syndrome, or ME/CFS, as well as fibromyalgia an...

A new biobehavioral model offers an opportunity to reduce nociplastic pain associated with anger regulation. https://www.practicalpainmanagement.com/news/anger-may-drive-subtype-of-chronic-pain At the intersection of anger, chronic pain, and the brain: A mini-review Bottom line: anger and an angry d...

A University at Buffalo expert on the behavioral treatment of chronic pain disorders has been awarded $3.3 million from the National Institutes of Health to conduct a five-year clinical study of drug-free behavioral treatments for chronic pelvic pain in men and women. More: https://www.buffalo.edu/n...

Men with CP/CPPS have a diverse set of neuroinflammatory genes with differential expression compared to controls. Clinical phenotypes have distinct patterns of gene expression. https://pubmed.ncbi.nlm.nih.gov/34532258/ Completely logical findings; it was always going to be the case that UCPPS patie...

Scientists in Israel say they have observed exactly how the brain can make the body sick — and believe tweaks in the behavior of gray matter could stop inflammation in the bowel, colon and elsewhere. Researchers at at the Technion-Israel Institute of Technology activated certain combinations of neu...

Interesting question and answer from Reddit: I went to Malone Lee’s clinic in London and spoke to one of his doctors. He told me that there was an embedded infection caught in biofilm. I’ve read his book on cystitis, and understand the theory. But here’s the thing, their diagnosis was based on the p...